7 Polysaccharides from reishi mushrooms and other types of folk-medicinal fungi are patented in Japan for use as immunomodulators in the treatment of cancer. 6 It is used by some cancer surgeons in Japan to treat patients significant anti-tumor and immunostimulation effects have been noted in many of these cases. Triterpene compounds - known as ganoderic acids, have been shown to lower blood pressure, reduce platelet stickiness and may decrease LDL-cholesterol 5Ĭlinical Application and Mechanism of ActionĪnti-Cancer Agent - Cancer studies in animals have shown a 50 percent tumor regression rate with reishi mushroom extract treatment (e.g., connective tissue cancer model in mice).These agents possess immune-modulating and anti-cancer properties 3 Specific polysaccharides - which occur in the form of beta-D-glucans bound to amino acids.Reishi mushrooms contain a number of active agents known to modulate function of the immune system in humans. 3 The fruiting body of the mushroom is used in medicines. 1,2 In recent years, its active ingredients have been the subject of intensive research regarding their apparent ability to help prevent or treat certain types of cancer liver disease HIV infection acute or recurrent herpetic infections high blood pressure chronic bronchitis allergies and asthma and to favorably modulate immune function. It has been used in Oriental medicine for over 2,000 years. Reishi mushroom (ganoderma lucidum) is called the "mushroom of immortality" in China, where it grows wild on decaying logs and tree stumps in the coastal provinces.
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